Publications

Wessels, D., D.F. Lusche, S. Kuhl, A. Scherer, E. Voss, and D.R. Soll. (2016) Quantitative Motion Analysis in Two and Three Dimensions. Methods in Molecular Biology. 1365:265-292

Kuhl, S., E. Voss, A. Scherer, D.F. Lusche, D. Wessels, and D.R. Soll. (2016) 4D Tumorigenesis Model for Quantitating Coalescence, Directed Cell Motility and Chemotaxis, Identifying Unique Cell Behaviors and Testing Anti-cancer Drugs. In Chemotaxis: Methods and Protocols. Hereld and Tian, eds.

Ambrose, J., M. Livitz, D. Wessels, S. Kuhl, D.F. Lusche, A. Scherer, E. Voss, and D.R. Soll. (2015) Mediated coalescence: a possible mechanism for tumor cellular heterogeneity. American Journal of Cancer Research. 5:3485-3504

Scherer, A., S. Kuhl, D. Wessels, D.F. Lusche, B. Hanson, J. Ambrose, E. Voss, E. Fletcher, C. Goldman, and D.R. Soll. (2015) A Computer-Assisted 3D Model for Analyzing the Aggregation of Tumorigenic Cells Reveals Specialized Behaviors and Unique Cell Types that Facilitate Aggregate Coalescence. PLoS ONE. 10:e0118628

Lusche, D.F., D. Wessels, N.A. Richardson, K.B. Russell, B.M. Hanson, B.A. Soll, B.H. Lin, and D.R. Soll. (2014) PTEN Redundancy: Overexpressing lpten, a homolog of Dictyostelium discoideum ptenA, the ortholog of human PTEN, rescues all behavioral defects of the mutant ptenA-. PLoS ONE. 9:e108495

Biggs LC, Naridze RL, DeMali KA, Lusche DF, Kuhl S, Soll DR, Schutte BC, Dunnwald M (2014) Interferon regulatory factor 6 regulates keratinocyte migration. Journal of cell science 127: 2840-2848

Wessels D, Lusche DF, Steimle PA, Scherer A, Kuhl S, Wood K, Hanson B, Egelhoff TT, Soll DR (2012) Myosin heavy chain kinases play essential roles in Ca2+, but not cAMP, chemotaxis and the natural aggregation of Dictyostelium discoideumJournal of cell science 125: 4934-4944

Lusche DF, Wessels D, Scherer A, Daniels K, Kuhl S, Soll DR (2012) The IplA Ca2+ channel of Dictyostelium discoideum is necessary for chemotaxis mediated through Ca2+, but not through cAMP, and has a fundamental role in natural aggregation. Journal of Cell Science 125: 1770-1783

Lusche DF, Wessels D, Ryerson DE, Soll DR (2011) Nhe1 is essential for potassium but not calcium facilitation of cell motility and the monovalent cation requirement for chemotactic orientation in Dictyostelium discoideumEukaryotic cell 10: 320-331

Breshears LM, Wessels D, Soll DR, Titus MA (2010) An unconventional myosin required for cell polarization and chemotaxis. Proceedings of the National Academy of Sciences of the United States of America 107: 6918-6923

Scherer A, Kuhl S, Wessels D, Lusche DF, Raisley B, Soll DR (2010) Ca2+ chemotaxis in Dictyostelium discoideumJournal of cell science 123: 3756-3767

Soll DR, Wessels D, Kuhl S, Lusche DF (2009) How a cell crawls and the role of cortical myosin II. Eukaryotic cell 8: 1381-1396

Lusche DF, Wessels D, Soll DR (2009) The effects of extracellular calcium on motility, pseudopod and uropod formation, chemotaxis, and the cortical localization of myosin II in Dictyostelium discoideumCell motility and the Cytoskeleton 66: 567-587

Wessels D, Kuhl S, Soll DR (2009) 2D and 3D quantitative analysis of cell motility and cytoskeletal dynamics. Methods in Molecular Biology 586: 315-335

Volk AP, Heise CK, Hougen JL, Artman CM, Volk KA, Wessels D, Soll DR, Nauseef WM, Lamb FS, Moreland JG (2008) ClC-3 and IClswell are required for normal neutrophil chemotaxis and shape change. J Biol Chem 283: 34315-34326

Sidani M, Wessels D, Mouneimne G, Ghosh M, Goswami S, Sarmiento C, Wang W, Kuhl S, El-Sibai M, Backer JM, Eddy R, Soll D, Condeelis J (2007) Cofilin determines the migration behavior and turning frequency of metastatic cancer cells. The Journal of cell biology 179: 777-791

Soll, D.R., E. Voss, D. Wessels, and S. Kuhl. (2007) Computer-Assisted Systems for Dynamic 3D Reconstruction and Motion Analysis of Living Cells. In Imaging Cellular and Molecular Biological Functions. S. Shorte and F. Frischknecht, editors. Springer Berlin Heidelberg. 365-384.

Wessels D, Lusche DF, Kuhl S, Heid P, Soll DR (2007) PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis. Journal of cell science 120: 2517-2531

Wessels D, Kuhl S, Soll DR (2006) Application of 2D and 3D DIAS to motion analysis of live cells in transmission and confocal microscopy imaging. Methods in Molecular Biology (Clifton, NJ) 346: 261-279

Heid PJ, Geiger J, Wessels D, Voss E, Soll DR (2005) Computer-assisted analysis of filopod formation and the role of myosin II heavy chain phosphorylation in DictyosteliumJournal of Cell Science 118: 2225-2237

Geiger J, Wessels D, Soll DR (2003) Human polymorphonuclear leukocytes respond to waves of chemoattractant, like Dictyostelium. Cell motility and the cytoskeleton 56: 27-44

Lockhart SR, Zhao R, Daniels KJ, Soll DR (2003) Alpha-pheromone-induced "shmooing" and gene regulation require white-opaque switching during Candida albicans mating. Eukaryotic cell 2: 847-855

Soll DR, Wessels D, Heid PJ, Voss E (2003) Computer-assisted reconstruction and motion analysis of the three-dimensional cell. ScientificWorldJournal 3: 827-841

Soll, D.R., D. Wessels, P.J. Heid, and H. Zhang. (2002) A contextual framework for characterizing motility and chemotaxis mutants in Dictyostelium discoideum. Journal of Muscle Research and Cell Motility. 23:659-672

Heid PJ, Voss E, Soll DR (2002) 3D-DIASemb: a computer-assisted system for reconstructing and motion analyzing in 4D every cell and nucleus in a developing embryo. Developmental Biology 245: 329-347

Soll, D.R., D. Wessels, E. Voss, and O. Johnson. (2001) Computer-assisted systems for the analysis of amoeboid cell motility. Methods in molecular biology. 161:45-58

Soll DR, Voss E, Johnson O, Wessels D (2000) Three-dimensional reconstruction and motion analysis of living, crawling cells. Scanning 22: 249-257

Soll DR (1999) Computer-assisted three-dimensional reconstruction and motion analysis of living, crawling cells. Computerized medical imaging and graphics: the official journal of the Computerized Medical Imaging Society. 23: 3-14

Soll D, Voss E (1998) Two and three dimensional computer systems for analyzing how cells crawl. In Motion Analysis of Living Cells, Soll D, Wessels D (eds), pp pp.25-52. John Wiley, Inc.

Wessels, D., and D.R. Soll. (1998) Computer-assisted characterization of the behavioral defects of cytoskeletal mutants of Dictyostelium discoideum. In Motion Analysis of Living Cells. D. Soll and D. Wessels, editors. John Wiley, Inc. 101-140.

Soll DR (1995) The use of computers in understanding how animal cells crawl. Int Rev Cytol 163: 43-104